Coldfusion stores Data source definitions here

Coldfusion server reinstallation or cloning is a common scenario however if your server is the type with multiple data sources, recreating those DSNs could be hell on earth – especially when you have a world cup match to watch.

All you need do is back-up of CFROOTruntimebinneo-datasources.xml. This XML file is where CF stores the data source settings for all DSNs. Mind you, the passwords are encrypted.